Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214049 | 0.86 | RAB9A (0.49) | DEGS1PTGS1NPC1RAB9A | |
| SCHEMBL2360146 | 0.81 | TEK (0.49) | KDRTEK | |
| SCHEMBL2324455 | 0.80 | TEK (0.55) | KIF11TEKCA12CA9 | |
| SCHEMBL212774 | 0.80 | ACHE (0.45) | DEGS1NPC1RAB9A | |
| SCHEMBL2360453 | 0.78 | WNT3A (0.42) | TEKNPC1RAB9A | |
| SCHEMBL2320060 | 0.78 | DEGS1 (0.45) | DEGS1KDRTEKNPC1RAB9A | |
| SCHEMBL2359964 | 0.77 | DEGS1 (0.46) | KIF11DEGS1PTGS1KDRTEK | |
| SCHEMBL5429627 | 0.75 | KIF11 (0.57) | KIF11 | |
| SCHEMBL6235808 | 0.75 | KIF11 (0.65) | KIF11 | |
| SCHEMBL4414108 | 0.75 | KIF11 (0.47) | KIF11CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |