Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.67 |
| ▸ | ACHE | P22303 | 6/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375216 | 0.83 | HRH3 (0.67) | HRH3ACHEMEN1KMT2AMLNR | |
| SCHEMBL1978437 | 0.79 | LMNA (0.61) | HRH3ALDH1A1RAB9A | |
| SCHEMBL8275450 | 0.79 | HRH3 (0.76) | HRH3ACHEALDH1A1MEN1KMT2A | |
| SCHEMBL8252094 | 0.79 | HRH3 (0.76) | HRH3ACHEPARP1HTR7ALDH1A1 | |
| SCHEMBL156202 | 0.79 | HRH3 (0.76) | HRH3ACHEALDH1A1MEN1RAB9A | |
| SCHEMBL6975680 | 0.77 | HRH3 (0.73) | HRH3ACHEHTR7ALDH1A1 | |
| SCHEMBL3861163 | 0.77 | HRH3 (0.73) | HRH3ACHEPARP1HTR7ALDH1A1 | |
| SCHEMBL3004249 | 0.77 | HRH3 (0.73) | HRH3ACHEPARP1HTR7ALDH1A1 | |
| SCHEMBL5411899 | 0.77 | HRH3 (0.73) | HRH3ACHE | |
| SCHEMBL156315 | 0.77 | ACHE (1.00) | HRH3ACHEHTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |