Sugi Predict

Sugi Predict / Compounds / SCHEMBL2359995

SCHEMBL2359995

SCHEMBL2359995

Nc1ccn(-c2cccc(F)c2F)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ RXRA P19793 4/20 0.38
▸ GRIN1 Q05586 3/20 0.38
▸ GRIN2B Q13224 3/20 0.38
▸ HCAR1 Q9BXC0 2/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ REV1 Q9UBZ9 1/20 0.35
▸ ADORA1 P30542 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ CES2 O00748 1/20 0.33
▸ BCHE P06276 1/20 0.33
▸ CES1 P23141 1/20 0.33
▸ HTR2A P28223 1/20 0.31
▸ HTR2C P28335 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29571922 1.00 MEN1 (0.42) MEN1KMT2AALDH1A1RXRAGRIN1
SCHEMBL403403 0.85 MEN1 (0.49) MEN1KMT2AALDH1A1HCAR1L3MBTL1
SCHEMBL29572416 0.85 MEN1 (0.49) MEN1KMT2AALDH1A1HCAR1L3MBTL1
Hydrochloric Acid SCHEMBL5958352 0.84 MEN1 (0.47) MEN1KMT2AALDH1A1HCAR1L3MBTL1
SCHEMBL15639281 0.83 IDO1 (0.40) MEN1KMT2AALDH1A1RXRAGRIN1
SCHEMBL15639432 0.79 ALDH1A1 (0.46) MEN1KMT2AALDH1A1L3MBTL1REV1
SCHEMBL29572653 0.76 ALDH1A1 (0.38) MEN1KMT2AALDH1A1RXRAGRIN1
SCHEMBL15639292 0.76 ALDH1A1 (0.38) MEN1KMT2AALDH1A1RXRAGRIN1
SCHEMBL29572092 0.74 ALDH1A1 (0.38) MEN1KMT2AALDH1A1L3MBTL1HTR2A
SCHEMBL15638709 0.74 ALDH1A1 (0.38) MEN1KMT2AALDH1A1L3MBTL1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548854-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2023-01-10 — — US disclosed
US-11548854-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2023-01-10 — — US disclosed
US-11332448-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2022-05-17 — — US disclosed
US-11332448-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2022-05-17 — — US disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 — — CN disclosed
CN-113243374-A Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-08-13 — — CN disclosed
CN-108477173-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-07-02 — — CN disclosed
US-10961201-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2021-03-30 — — US disclosed
US-10961201-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2021-03-30 — — US disclosed
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-02-25 — — US disclosed
EP-2903440-B1 HETEROCYCLIC COMPOUNDS AS PEST CONTROLLING AGENTS BAYER CROPSCIENCE AG (DE) 2017-09-06 — — EP disclosed
CN-105101800-A Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG 2015-11-25 — — CN disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 — — EP disclosed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 — — WO disclosed
US-20110230497-A1 BIOLOGICALLY ACTIVE AMIDES H. LUNDBECK A/S (DK) 2011-09-22 — — US disclosed
EP-2352730-A2 BIOLOGICALLY ACTIVE AMIDES H. Lundbeck A/S (DK) 2011-08-10 — — EP disclosed
WO-2010053861-A2 BIOLOGICALLY ACTIVE AMIDES H. LUNDBECK A/S (DK) 2010-05-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961201-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885
US-20110230497-A1 BIOLOGICALLY ACTIVE AMIDES NPY5R, NPY1R, NPY2R MEN1 2360/4885KMT2A 3489/4885ALDH1A1 3024/4885
US-11548854-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885
US-11332448-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.