Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572416 | 1.00 | MEN1 (0.49) | MEN1KMT2AALDH1A1ADORA1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5958352 | 0.98 | MEN1 (0.47) | MEN1KMT2AALDH1A1ADORA1CYP1A2 | |
| SCHEMBL2359995 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1ADORA1CYP1A2 | |
| SCHEMBL29571922 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1ADORA1CYP1A2 | |
| SCHEMBL5958455 | 0.80 | LMNA (0.41) | MEN1KMT2AALDH1A1ADORA1L3MBTL1 | |
| SCHEMBL5958426 | 0.80 | LMNA (0.41) | MEN1KMT2AALDH1A1ADORA1L3MBTL1 | |
| SCHEMBL15639432 | 0.78 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL2359645 | 0.78 | L3MBTL1 (0.41) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL29572188 | 0.78 | L3MBTL1 (0.41) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL2357923 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526098-B1 | NITROGEN-CONTAINING HETEROARYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-07-11 | — | — | EP | claimed |
| US-8470820-B2 | Nitrogen-containing heteroaryl derivatives | HOFFMAN-LA ROCHE INC. (US) | 2013-06-25 | — | — | US | claimed |
| US-11548854-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2023-01-10 | — | — | US | disclosed |
| US-11332448-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2022-05-17 | — | — | US | disclosed |
| CN-113243374-B | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-113243374-A | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-108477173-B | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2021-07-02 | — | — | CN | disclosed |
| US-10961201-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2021-03-30 | — | — | US | disclosed |
| US-20210053924-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-02-25 | — | — | US | disclosed |
| US-20210017136-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-01-21 | — | — | US | disclosed |
| US-10689348-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2020-06-23 | — | — | US | disclosed |
| US-7304072-B2 | E.g.,cis-N-(4-benzoylphenyl)-4-hydroxy-3'-oxospiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-carboxamide; useful as neuropeptide Y receptor antagonists and as agents for therapy of cardiovascular disorders, central nervous system disorders, metabolic diseases, respiratory and urogenital disorders | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |
| WO-2007016028-A2 | SYNTHESIS AND CRYSTALLINE FORMS OF NPY5 ANTAGONIST | MERCK & CO., INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| CN-1708483-A | Process for preparing pyrazole compounds | BANYU PHARMA CO LTD (JP) | 2005-12-14 | — | — | CN | disclosed |
| EP-1554251-A1 | PROCESS FOR MAKING PYRAZOLE COMPOUNDS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20050032820-A1 | Novel spiro compounds | MSD K.K. (JP) | 2005-02-10 | — | — | US | disclosed |
| WO-2003076443-A9 | SPIRO COMPOUNDS WITH NPY ANTAGONISTIC ACTIVITY | BANYU PHARMA CO LTD (JP) | 2005-01-20 | — | — | WO | disclosed |
| US-6803372-B2 | SUCH AS CIS-N-(4-BENZOYLPHENYL)-4-HYDROXY-3'-OXOSPIRO (CYCLOHEXANE-1,1' (3'H)-ISOBENZOFURAN)-4-CARBOXAMIDE FOR USE AS NEUROPEPTIDE Y RECEPTOR ANTAGONIST FOR TREATMENT BULIMIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-10-12 | — | — | US | disclosed |
| WO-2004037794-A1 | PROCESS FOR MAKING PYRAZOLE COMPOUNDS | BANYU PHARMACEUTICAL CO., LTD (JP) | 2004-05-06 | — | — | WO | disclosed |
| US-20020188124-A1 | Such as cis-N-(4-benzoylphenyl)-4-hydroxy-3'-oxospiro (cyclohexane-1,1' (3'H)-isobenzofuran)-4-carboxamide for use as neuropeptide Y receptor antagonist for treatment bulimia, obesity or diabetes | MSD K.K. (JP) | 2002-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961201-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885 |
| US-20020188124-A1 | Such as cis-N-(4-benzoylphenyl)-4-hydroxy-3'-oxospiro (cyclohexane-1,1' (3'H)-isobenzofuran)-4-carboxamide for use as neuropeptide Y receptor antagonist for treatment bulimia, obesity or diabetes | NPY1R, GPR119, NPY2R | MEN1 720/4885KMT2A 2001/4885ALDH1A1 2469/4885 |
| US-10689348-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885 |
| US-11548854-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885 |
| US-20210053924-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885 |
| US-20050032820-A1 | Novel spiro compounds | NR3C2, GPR119, NPY2R | MEN1 1284/4885KMT2A 2619/4885ALDH1A1 1517/4885 |
| US-11332448-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885 |
| US-20210017136-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | MEN1 2069/4885KMT2A 2247/4885ALDH1A1 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.