SCHEMBL236001

SCHEMBL236001

O=c1nc(NCO)cc[nH]1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
PARP1 P09874 1/20 0.32
DYRK1A Q13627 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
JAK2 O60674 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3680113 0.85 POLB (0.41) ALDH1A1POLBDYRK1AJAK2
SCHEMBL8143696 0.83 PARP1 (0.45) PARP1
SCHEMBL30695877 0.81
SCHEMBL19692262 0.80 ALDH1A1 (0.33) ALDH1A1POLBDYRK1AADORA2AADORA1
SCHEMBL17372301 0.80 ALDH1A1 (0.33) ALDH1A1POLBDYRK1AADORA2AADORA1
SCHEMBL65489 0.80 CACNA1C (0.42) ALDH1A1POLBADORA2AADORA1
SCHEMBL155989 0.79 PRKDC (0.42)
SCHEMBL6551974 0.79 NUDT1 (0.43) ALDH1A1POLB
SCHEMBL6379848 0.77 ZAP70 (0.39) ALDH1A1DYRK1A
SCHEMBL3219798 0.77 ALDH1A1 (0.35) ALDH1A1POLBADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2117 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070361-A Method for amplifying methylated DNA 辛戴克斯生物有限公司 2026-05-19 CN claimed
WO-2026090123-A1 METHODS AND COMPOSITIONS FOR MANAGING PESTS UOVO INTERNATIONAL LLC (US) 2026-04-30 WO claimed
WO-2026087976-A1 METHOD FOR DETECTING CANCER THROUGH CELL-FREE DNA METHYLATION PATTERNS IN SUBJECT AND DIAGNOSTIC DEVICE THEREFOR STRAND LIFE SCIENCES PRIVATE LIMITED (IN) 2026-04-30 WO claimed
US-12473596-B2 Delaying real-time sequencing PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2025-11-18 US claimed
US-12467082-B2 Selective oxidation of 5-methylcytosine by tet-family proteins THE CHILDREN'S MEDICAL CENTER CORPORATION 2025-11-11 US claimed
WO-2025224162-A1 NOVEL RECOMBINANT TET3 ENZYMES QUGEN GMBH (DE) 2025-10-30 WO claimed
EP-4640827-A1 RECOMBINANT TET3 ENZYMES Ludwig-Maximilians-Universität München (DE) 2025-10-29 EP claimed
EP-4617375-A2 METHODS, COMPOSITIONS AND SYSTEMS FOR IMPROVING THE BINDING OF METHYLATED POLYNUCLEOTIDES Guardant Health, Inc. (US) 2025-09-17 EP claimed
WO-2025137620-A1 METHODS FOR HIGH QUALITY AND HIGH ACCURACY METHYLATION SEQUENCING GUARDANT HEALTH, INC. (US) 2025-06-26 WO claimed
US-20250188546-A1 COMPOSITIONS AND METHODS FOR ANALYZING DNA USING PARTITIONING AND BASE CONVERSION GUARDANT HEALTH, INC. 2025-06-12 US claimed
US-8206935-B2 Method of rapidly quantifying hydroxymethylated DNA LI WEIWEI (US) 2012-06-26 US claimed
US-20120064521-A1 DETECTION OF DNA HYDROXYMETHYLATION ZYMO RESEARCH CORPORATION 2012-03-15 US claimed
US-20120003663-A1 Method of rapidly quantifying hydroxymethylated DNA LI WEIWEI (US) 2012-01-05 US claimed
WO-2011127136-A1 COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5-HYDROXYMETHYLCYTOSINE (5-HMC) UNIVERSITY OF CHICAGO (US) 2011-10-13 WO claimed
US-20110236894-A1 SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINS IMMUNE DISEASE INSTITUTE, INC. (US) 2011-09-29 US claimed
US-7833769-B2 McrA variants and uses thereof NEW ENGLAND BIOLABS, INC. (US) 2010-11-16 US claimed
WO-2010037001-A2 SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINS IMMUNE DISEASE INSTITUTE, INC. (US) 2010-04-01 WO claimed
CN-101132795-A Compounds useful in the treatment of HIV MEDIVIR AB (SE) 2008-02-27 CN claimed
WO-2003057822-A9 MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY OPTIMAL PRESENTATION OF 5' ENDS HYBRIDON INC (US) 2004-07-01 WO claimed
US-4029768-A Composition for application to the animal brain for synthesis of brain components involved in the learning process, and method PENN NATHAR W 1977-06-14 US claimed