Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 4/20 | 0.42 |
| ▸ | DGKA | P23743 | 2/20 | 0.40 |
| ▸ | DGKZ | Q13574 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526945 | 1.00 | MEN1 (0.43) | MEN1KMT2ASCDDGKADGKZ | |
| SCHEMBL23527049 | 0.90 | DGKA (0.40) | SCDDGKADGKZCHRM4 | |
| SCHEMBL31133713 | 0.90 | DGKZ (0.43) | SCDDGKADGKZCHRM4EPHX2 | |
| SCHEMBL23526830 | 0.90 | DGKZ (0.43) | SCDDGKADGKZCHRM4EPHX2 | |
| SCHEMBL23527107 | 0.89 | GPR6 (0.43) | SCDDGKADGKZCHRM4 | |
| SCHEMBL31133689 | 0.89 | GPR6 (0.43) | SCDDGKADGKZCHRM4 | |
| SCHEMBL31133702 | 0.89 | DGKA (0.44) | SCDDGKADGKZCHRM4EPHX2 | |
| SCHEMBL23527014 | 0.89 | DGKA (0.44) | SCDDGKADGKZCHRM4EPHX2 | |
| SCHEMBL23527156 | 0.88 | DGKA (0.41) | MEN1KMT2ASCDDGKADGKZ | |
| SCHEMBL23527221 | 0.88 | CHRM4 (0.47) | SCDDGKADGKZACSL1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081523-B1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2024-12-25 | — | — | EP | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | disclosed |