SCHEMBL23600960

SCHEMBL23600960

Cc1cccc(-c2ccc(C(C)(C)C)cc2)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.56
CCR8 P51685 1/20 0.56
CYP2A6 P11509 1/20 0.49
RAB9A P51151 4/20 0.45
ALDH1A1 P00352 4/20 0.45
NPC1 O15118 3/20 0.45
MAPT P10636 3/20 0.45
HPGD P15428 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
KIF11 P52732 2/20 0.44
TNF P01375 1/20 0.44
NOD1 Q9Y239 1/20 0.44
KDR P35968 1/20 0.43
EPHB4 P54760 1/20 0.43
TEK Q02763 1/20 0.43
BRS3 P32247 1/20 0.42
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.41
TGFBR1 P36897 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3625369 0.88 RAB9A (0.52) RAB9AALDH1A1NPC1MAPTHPGD
SCHEMBL3422361 0.85 CCR1 (0.75) CCR1CCR8CYP2A6RAB9AALDH1A1
SCHEMBL26233974 0.83 CCR1 (0.54) CCR1CCR8CYP2A6MAPTKIF11
SCHEMBL2615265 0.83 CCR1 (0.54) CCR1CCR8CYP2A6KIF11
SCHEMBL27984694 0.82 RAB9A (0.64) RAB9AALDH1A1NPC1MAPTHPGD
SCHEMBL2614970 0.79 CCR1 (0.65) CCR1CCR8CYP2A6RAB9AALDH1A1
SCHEMBL12176975 0.79 ASIC3 (0.60) RAB9AALDH1A1NPC1MAPTHPGD
SCHEMBL14234908 0.78 KDR (0.53) RAB9AALDH1A1NPC1MAPTHPGD
SCHEMBL2189142 0.78 KMT2A (0.62) CCR1CCR8CYP2A6RAB9AALDH1A1
SCHEMBL647992 0.77 MEN1 (0.68) CCR1CCR8CYP2A6RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283515-B Direct cross coupling method of aryl fluoride and aryl bromide 南京工业大学 2024-05-28 CN disclosed
CN-116283515-A Direct cross coupling method of aryl fluoride and aryl bromide 南京工业大学 2023-06-23 CN disclosed
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed