Sugi Predict

Sugi Predict / Compounds / SCHEMBL2189142

SCHEMBL2189142

SCHEMBL2189142

Cc1cccc(-c2ccc(-c3ccccc3)cc2)n1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.62
▸ MEN1 O00255 4/20 0.62
▸ RAB9A P51151 2/20 0.62
▸ CCR1 P32246 1/20 0.62
▸ CCR8 P51685 1/20 0.62
▸ CYP2A6 P11509 1/20 0.58
▸ TGFBR1 P36897 1/20 0.53
▸ ASIC3 Q9UHC3 1/20 0.52
▸ GRM5 P41594 1/20 0.47
▸ HSD11B1 P28845 1/20 0.47
▸ NPC1 O15118 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ ALDH1A1 P00352 3/20 0.45
▸ MAPT P10636 2/20 0.45
▸ HPGD P15428 2/20 0.45
▸ POLB P06746 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647992 0.96 MEN1 (0.68) KMT2AMEN1RAB9ACCR1CCR8
SCHEMBL29963679 0.96 MEN1 (0.68) KMT2AMEN1RAB9ACCR1CCR8
Bromide SCHEMBL15901554 0.93 RAB9A (0.65) KMT2AMEN1RAB9ACCR1CCR8
SCHEMBL12594495 0.93 MEN1 (0.64) KMT2AMEN1RAB9ACCR1CCR8
SCHEMBL17932287 0.92 MEN1 (0.54) KMT2AMEN1RAB9ACCR1CCR8
SCHEMBL16189443 0.92 MEN1 (0.54) KMT2AMEN1RAB9ACCR1CCR8
SCHEMBL16189330 0.92 MEN1 (0.54) KMT2AMEN1RAB9ACCR1CCR8
SCHEMBL3422361 0.91 CCR1 (0.75) KMT2AMEN1RAB9ACCR1CCR8
SCHEMBL16189026 0.90 MEN1 (0.56) KMT2AMEN1RAB9ACCR1CCR8
SCHEMBL17932479 0.89 MEN1 (0.55) KMT2AMEN1RAB9ACCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 — — US disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 — — EP disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 — — EP disclosed
EP-3399005-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2023-05-31 — — EP disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 — — US disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 — — US disclosed
US-11482685-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-10-25 — — US disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 — — US disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 — — US disclosed
US-10892426-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-01-12 — — US disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 — — US disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 — — US disclosed
EP-2342305-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2011-07-13 — — EP disclosed
EP-2168576-A2 New utilities of tricyclic compounds Shionogi & Co., Ltd. (JP) 2010-03-31 — — EP disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 — — WO disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 — — WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 — — WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 — — WO disclosed
US-20080318958-A1 New utilities of tricyclic compounds ISHIZUKA NATSUKI 2008-12-25 — — US disclosed
US-20080318958-A1 New utilities of tricyclic compounds ISHIZUKA NATSUKI 2008-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM KMT2A 1980/4885MEN1 1148/4885RAB9A 2330/4885
US-20080318958-A1 New utilities of tricyclic compounds APOB, PON1, APOL1 KMT2A 3525/4885MEN1 3380/4885RAB9A 3868/4885
US-10892426-B2 Organic electroluminescent materials and devices OCIAD2, LMNB2, RUVBL2 KMT2A 3500/4885MEN1 3921/4885RAB9A 818/4885
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, MCM4, KCNMB4 KMT2A 1687/4885MEN1 1207/4885RAB9A 2627/4885
US-20110227049-A1 PHOSPHORESCENT MATERIALS PPIP5K2, PAICS, IP6K1 KMT2A 2328/4885MEN1 1812/4885RAB9A 519/4885
US-11482685-B2 Organic electroluminescent materials and devices EML4, MCM4, KCNMB4 KMT2A 1687/4885MEN1 1207/4885RAB9A 2627/4885
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CLTB, L1CAM KMT2A 1980/4885MEN1 1148/4885RAB9A 2330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.