Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909845 | 0.81 | FNTA (0.36) | DHODHPSDABCG2CSNK2A2CSNK2B | |
| SCHEMBL23601379 | 0.81 | FNTA (0.36) | DHODHPSDABCG2CSNK2A2CSNK2B | |
| SCHEMBL23601897 | 0.81 | MAT2A (0.33) | MAT2AEGFRCSNK2A2CSNK2B | |
| SCHEMBL23601374 | 0.80 | DHODH (0.37) | DHODHMAT2ACSNK2A2CSNK2B | |
| SCHEMBL23601273 | 0.77 | TDP1 (0.39) | DHODHMAT2AKDM4E | |
| SCHEMBL23601515 | 0.76 | SLC6A4 (0.32) | MAT2AEGFR | |
| SCHEMBL23601637 | 0.76 | DHODH (0.32) | DHODH | |
| SCHEMBL23601434 | 0.75 | FNTA (0.36) | PSDABCG2 | |
| SCHEMBL31169421 | 0.75 | FNTA (0.36) | PSDABCG2 | |
| SCHEMBL29909758 | 0.75 | ABCG2 (0.37) | DHODHABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |