Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.33 |
| ▸ | MAT2A | P31153 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601273 | 0.84 | TDP1 (0.39) | DHODHMAT2AHPGDF10 | |
| SCHEMBL23577248 | 0.81 | FNTA (0.38) | DHODHMAP4K4SLC22A12CSNK2A2CSNK2B | |
| SCHEMBL29909890 | 0.81 | FNTA (0.38) | DHODHMAP4K4SLC22A12CSNK2A2CSNK2B | |
| SCHEMBL23601520 | 0.80 | MCHR1 (0.37) | — | |
| SCHEMBL23601009 | 0.80 | DHODH (0.33) | DHODHCSNK2A2CSNK2BMAT2A | |
| SCHEMBL23600472 | 0.79 | KDM4E (0.34) | DHODH | |
| SCHEMBL23601515 | 0.77 | SLC6A4 (0.32) | MAT2A | |
| SCHEMBL23601707 | 0.77 | PDE5A (0.42) | DHODHCSNK2A2CSNK2B | |
| SCHEMBL23601637 | 0.77 | DHODH (0.32) | DHODH | |
| SCHEMBL23601897 | 0.77 | MAT2A (0.33) | CSNK2A2CSNK2BMAT2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |