Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601775 | 0.91 | MAT2A (0.31) | PARP15TNKS2PARP2 | |
| SCHEMBL23576946 | 0.90 | — | — | |
| SCHEMBL23577331 | 0.88 | MAPT (0.30) | MAPT | |
| SCHEMBL29909404 | 0.88 | MAPT (0.30) | MAPT | |
| SCHEMBL23601233 | 0.84 | PARP15 (0.31) | PARP15PARP10TNKS2PARP2 | |
| SCHEMBL23601353 | 0.84 | KMT2A (0.38) | PARP15PARP10TNKS2PARP2MEN1 | |
| SCHEMBL23601647 | 0.84 | TNIK (0.31) | — | |
| SCHEMBL24721295 | 0.83 | MAT2A (0.30) | — | |
| SCHEMBL31169431 | 0.83 | MAT2A (0.30) | — | |
| SCHEMBL23577577 | 0.82 | MAT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |