Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601004 | 0.91 | MAT2A (0.36) | KMT2APARP15TNKS2PARP2MEN1 | |
| SCHEMBL23601650 | 0.89 | MAPT (0.31) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL23601007 | 0.87 | MAPT (0.36) | KMT2APARP15PARP10TNKS2PARP2 | |
| SCHEMBL30961043 | 0.84 | MAPT (0.39) | PARP15PARP10TNKS2PARP2MAPT | |
| SCHEMBL23600977 | 0.84 | MAPT (0.39) | PARP15PARP10TNKS2PARP2MAPT | |
| SCHEMBL23601050 | 0.84 | PARP15 (0.34) | KMT2APARP15PARP10TNKS2PARP2 | |
| SCHEMBL23601251 | 0.82 | MAPT (0.35) | KMT2AMEN1POLBMAPTRXFP1 | |
| SCHEMBL23576693 | 0.79 | MAT2A (0.35) | KMT2APARP15TNKS2PARP2MEN1 | |
| SCHEMBL29909100 | 0.79 | MAT2A (0.35) | KMT2APARP15TNKS2PARP2MEN1 | |
| SCHEMBL23576963 | 0.79 | ABCG2 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |