Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721359 | 0.82 | KDM1A (0.35) | KDM1AL3MBTL1HSD17B1HSD17B2 | |
| SCHEMBL32663654 | 0.76 | HSD11B1 (0.46) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5156396 | 0.76 | KDM1A (0.43) | KDM1AALOX5APIDO1METAP2 | |
| SCHEMBL23601159 | 0.75 | KDM1A (0.41) | KDM1AIDO1METAP2KDM4E | |
| Bromide SCHEMBL4466442 | 0.75 | KDM1A (0.42) | KDM1AALOX5APIDO1METAP2 | |
| SCHEMBL12973163 | 0.74 | HSD17B1 (0.59) | KDM1AIDO1METAP2BCHEACHE | |
| SCHEMBL12797772 | 0.74 | CYP3A4 (0.59) | KDM1AIDO1METAP2BCHEACHE | |
| SCHEMBL3422110 | 0.72 | IDO1 (0.58) | KDM1AIDO1METAP2BCHEACHE | |
| SCHEMBL20924174 | 0.72 | KDM1A (0.68) | KDM1AIDO1METAP2 | |
| SCHEMBL4402515 | 0.72 | HSD17B1 (0.61) | KDM1AIDO1METAP2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |