Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 2/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721362 | 0.82 | RXRA (0.40) | MAP4K4F2R | |
| SCHEMBL23600941 | 0.76 | CCR1 (0.41) | IDO1METAP2KDM4E | |
| SCHEMBL23601158 | 0.75 | KDM1A (0.52) | KDM1AIDO1METAP2KDM4E | |
| SCHEMBL23601692 | 0.74 | AR (0.39) | KDM1ACHRNB4CHRNA3MAP4K4WNT3A | |
| SCHEMBL23601698 | 0.72 | CHRNB4 (0.38) | CHRNB4CHRNA3MAP4K4WNT3A | |
| SCHEMBL2757248 | 0.72 | MAP4K4 (0.46) | MAP4K4WNT3AENPP3IDO1METAP2 | |
| SCHEMBL4404645 | 0.72 | HSD17B1 (0.55) | KDM1AMAP4K4ENPP3IDO1METAP2 | |
| SCHEMBL23601916 | 0.71 | NOTUM (0.44) | KDM1AMAP4K4ENPP3GRIN2BIDO1 | |
| SCHEMBL13680468 | 0.69 | GRIN1 (0.53) | MAP4K4ENPP3GRIN2BIDO1METAP2 | |
| SCHEMBL4406991 | 0.69 | HSD17B1 (0.51) | KDM1AMAP4K4ENPP3IDO1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |