Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721002 | 0.82 | MAPK1 (0.35) | NPY5RKDM1A | |
| SCHEMBL23601694 | 0.76 | KDM1A (0.50) | KDM1AIDO1TNF | |
| SCHEMBL15262893 | 0.74 | PTGS1 (0.35) | TNF | |
| SCHEMBL23601157 | 0.74 | AURKA (0.42) | CYP11B2PDE10APIM1KCNH2 | |
| SCHEMBL23601152 | 0.71 | NISCH (0.40) | KDM1APDE10APIM1 | |
| SCHEMBL2406986 | 0.70 | CYP2D6 (0.41) | CYP11B2GRM5PIM1 | |
| SCHEMBL21831103 | 0.69 | NOTUM (0.39) | — | |
| SCHEMBL24721358 | 0.68 | ALOX5AP (0.38) | KDM1AKCNH2TNF | |
| SCHEMBL2629282 | 0.67 | DDB1 (0.36) | — | |
| SCHEMBL30740055 | 0.67 | FEN1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |