Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721550 | 0.81 | ALOX5AP (0.37) | KDM1APDE10AALOX5APFEN1 | |
| SCHEMBL23601157 | 0.76 | AURKA (0.42) | PIM1PDE10A | |
| SCHEMBL17408899 | 0.73 | TGFBR1 (0.37) | NISCHPIM1TGFBR1DHODH | |
| SCHEMBL23601165 | 0.73 | FEN1 (0.41) | ALOX5APFEN1 | |
| SCHEMBL8360921 | 0.72 | DHODH (0.43) | NISCHPIM1TGFBR1KDM1ADHODH | |
| SCHEMBL23601694 | 0.72 | KDM1A (0.50) | NISCHKDM1A | |
| SCHEMBL23601162 | 0.71 | CYP11B1 (0.34) | PIM1KDM1APDE10A | |
| SCHEMBL16502032 | 0.70 | PTGS2 (0.40) | NISCHPIM1TGFBR1KDM1ADHODH | |
| SCHEMBL14988315 | 0.70 | KDM1A (0.43) | NISCHPIM1TGFBR1KDM1ADHODH | |
| SCHEMBL24721358 | 0.70 | ALOX5AP (0.38) | KDM1AALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |