SCHEMBL23601318 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	PDGFRB	P09619	2/20	0.38

▸	MAT2A	P31153	9/20	0.37

▸	EGFR	P00533	5/20	0.36

▸	KDR	P35968	1/20	0.36

▸	PRMT5	O14744	3/20	0.35

▸	CSNK2A2	P19784	1/20	0.34

▸	CSNK2B	P67870	1/20	0.34

▸	CSF1R	P07333	1/20	0.33

▸	CYP1A2	P05177	1/20	0.33

▸	RXRA	P19793	1/20	0.33

▸	RXRB	P28702	1/20	0.33

▸	RXRG	P48443	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23601397	0.90	EGFR (0.38)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL23576826	0.88	PDGFRB (0.36)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL29909381	0.88	PDGFRB (0.36)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL24721479	0.87	PDGFRB (0.35)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL29909162	0.83	PDGFRB (0.38)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL24806307	0.83	MAPT (0.40)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL23577196	0.83	PDGFRB (0.38)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL23601319	0.81	EGFR (0.36)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL23576646	0.81	MAT2A (0.39)	PDGFRBMAT2AEGFRKDRPRMT5
SCHEMBL29909742	0.81	MAT2A (0.39)	PDGFRBMAT2AEGFRKDRPRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021130638-A1	DIACYLGLYCEROL KINASE MODULATING COMPOUNDS	CARNA BIOSCIENCES, INC. (JP)	2021-07-01	—	—	WO	disclosed