Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 8/20 | 0.35 |
| ▸ | EGFR | P00533 | 5/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576826 | 1.00 | PDGFRB (0.36) | PDGFRBMAT2AEGFRKDRPRMT5 | |
| SCHEMBL23601318 | 0.88 | PDGFRB (0.38) | PDGFRBMAT2AEGFRKDRPRMT5 | |
| SCHEMBL23601397 | 0.87 | EGFR (0.38) | PDGFRBMAT2AEGFRKDRPRMT5 | |
| SCHEMBL24721479 | 0.83 | PDGFRB (0.35) | PDGFRBMAT2AEGFRKDRPRMT5 | |
| SCHEMBL23601518 | 0.81 | MAT2A (0.33) | MAT2A | |
| SCHEMBL23576646 | 0.80 | MAT2A (0.39) | PDGFRBMAT2AEGFRKDRPRMT5 | |
| SCHEMBL29909742 | 0.80 | MAT2A (0.39) | PDGFRBMAT2AEGFRKDRPRMT5 | |
| SCHEMBL23601319 | 0.80 | EGFR (0.36) | PDGFRBMAT2AEGFRKDRPRMT5 | |
| SCHEMBL24806307 | 0.79 | MAPT (0.40) | PDGFRBMAT2AEGFRKDRPRMT5 | |
| SCHEMBL23577196 | 0.79 | PDGFRB (0.38) | PDGFRBMAT2AEGFRKDRPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |