Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12286276 | 0.86 | NAMPT (0.37) | RIPK1HDAC6NAMPTMEN1KMT2A | |
| SCHEMBL18867575 | 0.84 | ESR1 (0.42) | NAMPTMEN1KMT2AMAPTQDPR | |
| SCHEMBL17342894 | 0.82 | RIPK1 (0.33) | RIPK1HDAC6NAMPTMEN1KMT2A | |
| SCHEMBL16978139 | 0.81 | HDAC6 (0.44) | RIPK1HDAC6NAMPTHDAC8MEN1 | |
| SCHEMBL7687130 | 0.80 | NAMPT (0.53) | NAMPTMEN1KMT2AMAPTQDPR | |
| SCHEMBL8261115 | 0.79 | QDPR (0.49) | NAMPTMAPTQDPRALDH1A1 | |
| SCHEMBL17888233 | 0.77 | GRM1 (0.45) | NAMPTMEN1KMT2A | |
| SCHEMBL25799678 | 0.77 | GRM5 (0.45) | NAMPTALDH1A1NPC1RAB9A | |
| SCHEMBL8218881 | 0.77 | PDK4 (0.51) | NAMPT | |
| SCHEMBL17034783 | 0.77 | RIPK1 (0.42) | RIPK1HDAC6NAMPTHDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |