Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600472 | 0.84 | KDM4E (0.34) | DHODH | |
| SCHEMBL29909506 | 0.79 | ABCG2 (0.35) | DHODHABCG2PDE5A | |
| SCHEMBL23577238 | 0.79 | ABCG2 (0.35) | DHODHABCG2PDE5A | |
| SCHEMBL23601374 | 0.76 | DHODH (0.37) | DHODHF10 | |
| SCHEMBL23601707 | 0.76 | PDE5A (0.42) | DHODHABCG2PDE5A | |
| SCHEMBL23601250 | 0.74 | DHODH (0.33) | DHODHABCG2PDE5A | |
| SCHEMBL23601857 | 0.74 | DHODH (0.35) | DHODHABCG2PDE5A | |
| SCHEMBL23576887 | 0.72 | DHODH (0.40) | DHODHABCG2ICMT | |
| SCHEMBL29909316 | 0.72 | DHODH (0.40) | DHODHABCG2ICMT | |
| SCHEMBL23577282 | 0.72 | ABCG2 (0.33) | DHODHABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |