Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601857 | 0.91 | DHODH (0.35) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL23601587 | 0.87 | EGFR (0.34) | MEN1ALDH1A1KMT2ADHODH | |
| SCHEMBL23601376 | 0.84 | DHODH (0.36) | DHODH | |
| SCHEMBL23601250 | 0.81 | DHODH (0.33) | MAPTDHODH | |
| SCHEMBL29909022 | 0.81 | ASIC1 (0.33) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL23577116 | 0.81 | ASIC1 (0.33) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL23601374 | 0.79 | DHODH (0.37) | DHODH | |
| SCHEMBL23601707 | 0.78 | PDE5A (0.42) | DHODH | |
| SCHEMBL23601637 | 0.73 | DHODH (0.32) | DHODH | |
| SCHEMBL23601723 | 0.72 | PDE5A (0.36) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |