Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601723 | 0.93 | PDE5A (0.36) | PDE5A | |
| SCHEMBL23601069 | 0.89 | PDE5A (0.37) | PDE5ACSNK2A1CSNK2A2CSNK2BEGFR | |
| SCHEMBL23601722 | 0.87 | PDE5A (0.36) | PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601804 | 0.86 | CHEK1 (0.38) | PDE5ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL23601557 | 0.85 | LMNA (0.40) | DHODHEGFRPDGFRBKDR | |
| SCHEMBL23601391 | 0.85 | EGFR (0.46) | EGFRPDGFRBKDR | |
| SCHEMBL23601210 | 0.84 | PDE5A (0.36) | PDE5AABCG2DHODH | |
| SCHEMBL23601519 | 0.82 | ABCG2 (0.46) | ABCG2 | |
| SCHEMBL23601857 | 0.81 | DHODH (0.35) | PDE5AABCG2DHODH | |
| SCHEMBL23601197 | 0.80 | MAPT (0.43) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |