Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909868 | 0.85 | P2RY14 (0.38) | MCHR1P2RY14DRD2BRD4 | |
| SCHEMBL24721497 | 0.85 | P2RY14 (0.38) | MCHR1P2RY14DRD2BRD4 | |
| SCHEMBL23601515 | 0.84 | SLC6A4 (0.32) | — | |
| SCHEMBL23601374 | 0.80 | DHODH (0.37) | — | |
| SCHEMBL23601273 | 0.77 | TDP1 (0.39) | — | |
| SCHEMBL23576631 | 0.76 | MCHR1 (0.39) | MCHR1 | |
| SCHEMBL23600788 | 0.73 | CHEK2 (0.37) | — | |
| SCHEMBL23601009 | 0.72 | DHODH (0.33) | — | |
| SCHEMBL23600539 | 0.72 | MAT2A (0.35) | — | |
| SCHEMBL23601897 | 0.71 | MAT2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |