Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | XBP1 | P17861 | 4/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | TERT | O14746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carpesiolin SCHEMBL10099626 | 1.00 | MAPT (0.59) | MAPTRAB9ANPC1HTTXBP1 | |
| Carpesiolin SCHEMBL21214080 | 1.00 | MAPT (0.59) | MAPTRAB9ANPC1HTTXBP1 | |
| Carpesiolin SCHEMBL6425398 | 1.00 | MAPT (0.59) | MAPTRAB9ANPC1HTTXBP1 | |
| Carpesiolin SCHEMBL11891059 | 1.00 | MAPT (0.59) | MAPTRAB9ANPC1HTTXBP1 | |
| Ergolide SCHEMBL28262978 | 0.83 | PTGS2 (0.67) | MAPTRAB9ANPC1HTTXBP1 | |
| Carabrolactone B SCHEMBL30040355 | 0.78 | MAPT (0.54) | MAPTRAB9ANPC1HTTXBP1 | |
| Helenalin SCHEMBL161593 | 0.74 | MAPT (1.00) | MAPTRAB9ANPC1HTTXBP1 | |
| Helenalin SCHEMBL10132557 | 0.74 | MAPT (1.00) | MAPTRAB9ANPC1HTTXBP1 | |
| Helenalin SCHEMBL10099625 | 0.74 | MAPT (1.00) | MAPTRAB9ANPC1HTTXBP1 | |
| Helenalin SCHEMBL31237389 | 0.74 | MAPT (1.00) | MAPTRAB9ANPC1HTTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118924739-A | Medical application of pseudo-guaiane sesquiterpene derivatives | 南京中医药大学 | 2024-11-12 | — | — | CN | disclosed |
| US-20220401435-A1 | MRGPRX2 ANTAGONIST FOR THE TREATMENT OF PSEUDO ALLERGIC REACTIONS | THE UNIVERSITY OF HONG KONG | 2022-12-22 | — | — | US | disclosed |
| US-20210196676-A1 | TREATMENT OF VIRAL INFECTIONS AND VIRALLY ASSOCIATED LESIONS WITH SEQUITERPENE LACTONES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220401435-A1 | MRGPRX2 ANTAGONIST FOR THE TREATMENT OF PSEUDO ALLERGIC REACTIONS | MRGPRX2, MRGPRX1, MRGPRX4 | MAPT 4138/4885RAB9A 1773/4885NPC1 1490/4885 |
| US-20210196676-A1 | TREATMENT OF VIRAL INFECTIONS AND VIRALLY ASSOCIATED LESIONS WITH SEQUITERPENE LACTONES | CUTA, LTN1, HAVCR2 | MAPT 3547/4885RAB9A 4163/4885NPC1 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.