Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601061 | 0.90 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2LMNARXFP1MEN1 | |
| SCHEMBL23601005 | 0.86 | SMN1; SMN2 (0.33) | MAPTSMN1; SMN2LMNARXFP1 | |
| SCHEMBL23601007 | 0.83 | MAPT (0.36) | MAPTSMN1; SMN2LMNARXFP1MEN1 | |
| SCHEMBL23601581 | 0.80 | — | — | |
| SCHEMBL24721314 | 0.80 | — | — | |
| SCHEMBL23601890 | 0.78 | TP53 (0.39) | MAPTSMN1; SMN2LMNARXFP1MEN1 | |
| SCHEMBL23601730 | 0.76 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL23576882 | 0.75 | — | — | |
| SCHEMBL29909350 | 0.75 | — | — | |
| SCHEMBL23601241 | 0.75 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |