Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 6/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 6/20 | 0.32 |
| ▸ | PER2 | O15055 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601061 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTCRY1CRY2PER2 | |
| SCHEMBL23601672 | 0.86 | MAPT (0.35) | SMN1; SMN2MAPTLMNARXFP1 | |
| SCHEMBL23601471 | 0.85 | MAPT (0.31) | SMN1; SMN2MAPT | |
| SCHEMBL23601586 | 0.85 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTTP53 | |
| SCHEMBL23601457 | 0.85 | KDM4E (0.30) | — | |
| SCHEMBL23601469 | 0.84 | NQO2 (0.32) | — | |
| SCHEMBL23601010 | 0.83 | CRY1 (0.33) | SMN1; SMN2MAPTCRY1CRY2TP53 | |
| SCHEMBL23601007 | 0.83 | MAPT (0.36) | SMN1; SMN2MAPTLMNARXFP1 | |
| SCHEMBL23601511 | 0.83 | CRY1 (0.30) | CRY1CRY2 | |
| SCHEMBL23601667 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |