Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909815 | 0.88 | MAPT (0.33) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23577324 | 0.88 | MAPT (0.33) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23601353 | 0.87 | KMT2A (0.38) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23601061 | 0.87 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23578049 | 0.85 | ABCG2 (0.42) | SMN1; SMN2ABCG2 | |
| SCHEMBL23601004 | 0.84 | MAT2A (0.36) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23601005 | 0.83 | SMN1; SMN2 (0.33) | MAPTSMN1; SMN2LMNARXFP1 | |
| SCHEMBL23601672 | 0.83 | MAPT (0.35) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23601650 | 0.82 | MAPT (0.31) | MAPTSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL23577331 | 0.81 | MAPT (0.30) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |