Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 5/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601586 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTTP53MAT2APRMT5 | |
| SCHEMBL23601004 | 0.88 | MAT2A (0.36) | SMN1; SMN2MAPTTP53MAT2APRMT5 | |
| SCHEMBL23601061 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL23601771 | 0.82 | SMN1; SMN2 (0.31) | SMN1; SMN2MAPTTP53 | |
| SCHEMBL23601473 | 0.82 | TNIK (0.31) | — | |
| SCHEMBL23601420 | 0.82 | MAPT (0.33) | SMN1; SMN2MAPTTP53 | |
| SCHEMBL23577246 | 0.81 | — | — | |
| SCHEMBL29909179 | 0.79 | — | — | |
| SCHEMBL23601353 | 0.78 | KMT2A (0.38) | SMN1; SMN2MAPTTP53MEN1KMT2A | |
| SCHEMBL23577387 | 0.78 | MAT2A (0.36) | SMN1; SMN2MAPTTP53MAT2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |