Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577932 | 1.00 | GAA (0.36) | GAAMAPTIDO1NR4A2KMT2A | |
| SCHEMBL23577333 | 0.85 | EGFR (0.35) | NR4A2KMT2ALMNASMN1; SMN2MPO | |
| SCHEMBL30014065 | 0.85 | EGFR (0.35) | NR4A2KMT2ALMNASMN1; SMN2MPO | |
| SCHEMBL23601713 | 0.77 | CHKA (0.39) | GAAMAPTNR4A2KMT2ALMNA | |
| SCHEMBL23576849 | 0.76 | EGFR (0.41) | GAAMAPTKMT2ACHKA | |
| SCHEMBL29909472 | 0.76 | EGFR (0.41) | GAAMAPTKMT2ACHKA | |
| SCHEMBL23601276 | 0.76 | GAA (0.40) | GAAMAPTIDO1NR4A2KMT2A | |
| SCHEMBL30013543 | 0.76 | GAA (0.38) | GAAMAPTIDO1NR4A2KMT2A | |
| SCHEMBL30961048 | 0.76 | GAA (0.50) | GAAMAPTADORA1CHKA | |
| SCHEMBL23577187 | 0.76 | GAA (0.50) | GAAMAPTADORA1CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |