Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600941 | 0.76 | CCR1 (0.41) | ALDH1A1KDM4EOPRM1OPRL1IDO1 | |
| SCHEMBL23601813 | 0.74 | KDM4E (0.33) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL24721018 | 0.72 | CHRNA7 (0.37) | ALDH1A1IDO1TDO2 | |
| SCHEMBL21382098 | 0.72 | MEN1 (0.51) | ALDH1A1POLBKDM1AKCNH2RCOR1 | |
| SCHEMBL30863804 | 0.71 | — | — | |
| SCHEMBL14946800 | 0.69 | ALDH1A1 (0.39) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL2147572 | 0.69 | ADRA2A (0.37) | ALDH1A1KDM4EOPRM1OPRL1POLB | |
| SCHEMBL15611917 | 0.69 | ALDH1A1 (0.36) | ALDH1A1KDM4EOPRM1OPRL1ADRA2A | |
| SCHEMBL15627469 | 0.69 | KDM4E (0.32) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL23495205 | 0.69 | FDPS (0.40) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |