Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359029 | 0.85 | ERN1 (0.44) | ERN1PTGS2PTGS1TDP1MEN1 | |
| SCHEMBL14879484 | 0.83 | TDP1 (0.44) | ERN1PTGS2PTGS1HSD17B10TDP1 | |
| SCHEMBL387189 | 0.82 | XDH (0.51) | ERN1PTGS2PTGS1HSD17B10TDP1 | |
| SCHEMBL16399564 | 0.82 | LMNA (0.48) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL15742298 | 0.81 | ERN1 (0.48) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL9990065 | 0.81 | PTGS2 (0.40) | ERN1PTGS2PTGS1HSD17B10TDP1 | |
| SCHEMBL5735298 | 0.80 | ERN1 (0.52) | ERN1PTGS2PTGS1HSD17B10SLC6A4 | |
| SCHEMBL547471 | 0.80 | PTGS2 (0.39) | ERN1PTGS2PTGS1HSD17B10TDP1 | |
| SCHEMBL12523784 | 0.80 | ERN1 (0.36) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL2064769 | 0.79 | NR4A2 (0.69) | NR4A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |