Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576719 | 1.00 | PTAFR (0.32) | PTAFRBCHEACHEGRIN1GRIN2A | |
| SCHEMBL23601313 | 0.92 | PTAFR (0.33) | PTAFRBCHEACHEGRIN1GRIN2A | |
| SCHEMBL29909267 | 0.89 | DHODH (0.35) | PTAFR | |
| SCHEMBL23601964 | 0.89 | DHODH (0.35) | PTAFR | |
| SCHEMBL29909342 | 0.88 | DHODH (0.36) | PTAFR | |
| SCHEMBL23576692 | 0.88 | DHODH (0.36) | PTAFR | |
| SCHEMBL30047539 | 0.85 | PER2 (0.30) | PTAFR | |
| SCHEMBL24813167 | 0.85 | PER2 (0.30) | PTAFR | |
| SCHEMBL23601264 | 0.84 | DHODH (0.36) | PTAFRBCHEACHEGRIN1GRIN2A | |
| SCHEMBL23601078 | 0.83 | DHODH (0.39) | PTAFRBCHEACHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |