SCHEMBL236027

SCHEMBL236027

CNC(NC)c1ccccc1N[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 1/20 0.32
POLB P06746 2/20 0.31
ALDH1A1 P00352 2/20 0.31
RECQL P46063 2/20 0.31
MAPT P10636 2/20 0.31
ESR1 P03372 1/20 0.31
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28740915 0.82 L3MBTL1 (0.43) L3MBTL1TSHRPOLBALDH1A1RECQL
SCHEMBL18991348 0.77 L3MBTL1 (0.53) L3MBTL1TSHRPOLBRECQLMAPT
SCHEMBL235044 0.73 TSHR (0.35) TSHRESR1HSD17B10
SCHEMBL466037 0.68 GABRA1 (0.56) L3MBTL1TSHRPOLBALDH1A1RECQL
SCHEMBL18991270 0.64
SCHEMBL1485841 0.61 HTR2A (0.50) TSHRPOLBALDH1A1MAPTKDM4E
SCHEMBL2737240 0.61 L3MBTL1 (0.55) L3MBTL1TSHRPOLBALDH1A1RECQL
SCHEMBL24071120 0.59 MAPT (0.43) L3MBTL1TSHRPOLBALDH1A1RECQL
Hydrochloric Acid SCHEMBL2860733 0.59 L3MBTL1 (0.53) L3MBTL1TSHRPOLBALDH1A1RECQL
SCHEMBL16771466 0.59 L3MBTL1 (0.43) L3MBTL1TSHRPOLBALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed