Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202212 | 0.84 | NCF1 (0.43) | NCF1KDM4EALDH1A1NOS3NOS1 | |
| SCHEMBL26762571 | 0.83 | SIGMAR1 (0.36) | SIGMAR1NCF1MCHR1KDM4EALDH1A1 | |
| SCHEMBL23603446 | 0.81 | SIGMAR1 (0.40) | SIGMAR1NCF1MCHR1KDM4EALDH1A1 | |
| SCHEMBL25123178 | 0.80 | HRH3 (0.33) | MCHR1KDM4EALDH1A1 | |
| SCHEMBL10202213 | 0.79 | NCF1 (0.46) | NCF1KDM4EALDH1A1NOS3NOS1 | |
| SCHEMBL13046392 | 0.79 | KDM4E (0.41) | NCF1MCHR1KDM4EALDH1A1NOS3 | |
| SCHEMBL23588611 | 0.79 | PGR (0.38) | SIGMAR1NCF1MCHR1KDM4EALDH1A1 | |
| SCHEMBL12325953 | 0.79 | PGR (0.38) | SIGMAR1NCF1MCHR1KDM4EALDH1A1 | |
| SCHEMBL14186611 | 0.79 | PGR (0.38) | SIGMAR1NCF1MCHR1KDM4EALDH1A1 | |
| SCHEMBL772542 | 0.79 | SIGMAR1 (0.40) | SIGMAR1NCF1MCHR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021129653-A1 | PROTEIN DEGRADATION AGENT COMPOUND PREPARATION METHOD AND APPLICATION | 上海济煜医药科技有限公司 | 2021-07-01 | — | — | WO | disclosed |