SCHEMBL2360481

SCHEMBL2360481

O=C(NCC1CCNCC1)n1c(=O)[nH]c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 4/20 0.60
PLD2 O14939 1/20 0.45
PLD1 Q13393 1/20 0.45
HRH1 P35367 1/20 0.44
CCR3 P51677 1/20 0.44
KCNH2 Q12809 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18626130 0.84 PLD1 (0.49) HTR4PLD2PLD1HRH1CCR3
SCHEMBL18626125 0.83 HTR4 (0.45) HTR4PLD2PLD1HRH1CCR3
Hydrochloric Acid SCHEMBL7422509 0.80 KDM4E (0.58) HTR4PLD2PLD1
SCHEMBL2360688 0.78 HTR4 (0.73) HTR4
SCHEMBL2338407 0.77 HTR4 (0.69) HTR4
SCHEMBL2361077 0.76 HTR4 (0.71) HTR4
SCHEMBL2335357 0.75 HTR4 (1.00) HTR4
SCHEMBL20847333 0.75 HTR4 (0.43) HTR4PLD2PLD1HRH1CCR3
SCHEMBL7594782 0.73 DAO (0.44) PLD2PLD1HRH1CCR3KCNH2
SCHEMBL23997256 0.72 HPGD (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2358702-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK Holdings Co., Ltd. (KR) 2011-08-24 EP disclosed