Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PLD2 | O14939 | 1/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18626125 | 0.85 | HTR4 (0.45) | HTR4HRH1CCR3KCNH2PLD2 | |
| SCHEMBL18626130 | 0.78 | PLD1 (0.49) | HTR4HRH1CCR3KCNH2PLD2 | |
| SCHEMBL2360481 | 0.75 | HTR4 (0.60) | HTR4HRH1CCR3KCNH2PLD2 | |
| Hydrochloric Acid SCHEMBL7422509 | 0.74 | KDM4E (0.58) | HTR4PLD2PLD1 | |
| SCHEMBL5742996 | 0.66 | CCR3 (0.42) | HTR4HRH1CCR3KCNH2PLD2 | |
| SCHEMBL7599845 | 0.65 | DAO (0.47) | — | |
| SCHEMBL11275907 | 0.63 | DAO (0.51) | — | |
| SCHEMBL7536796 | 0.63 | ALDH1A1 (0.53) | HTR4 | |
| SCHEMBL2974917 | 0.63 | HTR4 (0.73) | HTR4 | |
| SCHEMBL8261242 | 0.63 | PLD2 (0.45) | HRH1CCR3KCNH2PLD2PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190092727-A1 | Piperidine Compounds, Pharmaceutical Composition Comprising The Same And Its Use | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092727-A1 | Piperidine Compounds, Pharmaceutical Composition Comprising The Same And Its Use | PGC, VIP, PIGO | HTR4 308/4885HRH1 15/4885CCR3 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.