Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 8/20 | 0.71 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360688 | 0.86 | HTR4 (0.73) | HTR4 | |
| SCHEMBL2335357 | 0.83 | HTR4 (1.00) | HTR4 | |
| SCHEMBL2338407 | 0.82 | HTR4 (0.69) | HTR4TMEM97SIGMAR1 | |
| SCHEMBL2360481 | 0.76 | HTR4 (0.60) | HTR4 | |
| SCHEMBL7336661 | 0.75 | HTR4 (0.46) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL8294935 | 0.75 | HTR4 (0.50) | HTR4 | |
| SCHEMBL2337246 | 0.75 | DRD4 (0.51) | TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7533240 | 0.74 | HTR4 (0.49) | HTR4 | |
| SCHEMBL3304360 | 0.73 | HTR4 (0.43) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL2335311 | 0.73 | LMNA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358702-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK Holdings Co., Ltd. (KR) | 2011-08-24 | — | — | EP | disclosed |