SCHEMBL236049

SCHEMBL236049

CCN(Cc1cnc(Cl)s1)C(=C[N+](=O)[O-])NC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
BMP1 P13497 1/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
PKM P14618 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7679007 1.00 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL236048 1.00 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL7662478 0.91 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL237009 0.89
SCHEMBL237010 0.89
SCHEMBL237725 0.88 ACHE (0.30) ACHE
SCHEMBL237726 0.88 ACHE (0.30) ACHE
SCHEMBL7670572 0.87 RECQL (0.35) RECQLMAPTPOLBGAABMP1
SCHEMBL2787317 0.87
SCHEMBL2787316 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2225940-B1 Oil dispersions of nAChR binding neonicotinoids GAT MICROENCAPSULATION GMBH (AT) 2014-03-12 EP disclosed
US-8293733-B2 Oil dispersions of nAChR binding neonicotinoids GAT MICROENCAPSULATION AG (AT) 2012-10-23 US disclosed
US-8293733-B2 Oil dispersions of nAChR binding neonicotinoids GAT MICROENCAPSULATION AG (AT) 2012-10-23 US disclosed
US-20120004104-A1 OIL DISPERSIONS OF nAChR BINDING NEONICOTINOIDS GAT MICROENCAPSULATION AG (AT) 2012-01-05 US disclosed
US-20120004104-A1 OIL DISPERSIONS OF nAChR BINDING NEONICOTINOIDS GAT MICROENCAPSULATION AG (AT) 2012-01-05 US disclosed
EP-2225940-A1 Oil dispersions of nAChR binding neonicotinoids GAT Microencapsulation AG (AT) 2010-09-08 EP disclosed
US-6500416-B2 FLUID FLOW; INSECTICIDE; MITICIDE SYNGENTA CROP PROTECTION, INC. 2002-12-31 US disclosed
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
CN-1085937-C A method of killing noxious insects BAYER AGROCHEM KK (JP) 2002-06-05 CN disclosed
US-20010021378-A1 Pesticide SYNGENTA CROP PROTECTION, INC. 2001-09-13 US disclosed
EP-0632957-A1 A method of killing noxious insects NIHON BAYER AGROCHEM K.K. (JP) 1995-01-11 EP disclosed
EP-0617890-A1 Synergistic insecticidal compositions NIHON BAYER AGROCHEM K.K. (JP) 1994-10-05 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5230893-A Pesticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-07-27 US disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
EP-0496106-A1 Stable agrochemical compositions Takeda Chemical Industries, Ltd. (JP) 1992-07-29 EP disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004104-A1 OIL DISPERSIONS OF nAChR BINDING NEONICOTINOIDS CHRND, ITGAM, CHRM2 RECQL 3472/4885MAPT 3809/4885POLB 3841/4885
US-20010021378-A1 Pesticide DDT, KISS1R, ACHE RECQL 1520/4885MAPT 1014/4885POLB 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.