Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | CHAT | P28329 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360504 | 1.00 | TRPA1 (0.38) | TRPA1KMT2APOLBPKMMAPK1 | |
| SCHEMBL97362 | 0.88 | POLB (0.37) | TRPA1KMT2APOLBPKMMAPK1 | |
| SCHEMBL97363 | 0.88 | POLB (0.37) | TRPA1KMT2APOLBPKMMAPK1 | |
| SCHEMBL14990171 | 0.85 | KCNA3 (0.39) | ALDH1A1NFE2L2CHATVCPMAOB | |
| SCHEMBL14990170 | 0.85 | KCNA3 (0.39) | ALDH1A1NFE2L2CHATVCPMAOB | |
| SCHEMBL11045499 | 0.82 | NFE2L2 (0.52) | TRPA1NFE2L2VCP | |
| SCHEMBL4498689 | 0.82 | ALDH1A1 (0.54) | KMT2AALDH1A1CHATNPSR1PYGL | |
| SCHEMBL11045502 | 0.82 | NFE2L2 (0.52) | TRPA1NFE2L2VCP | |
| SCHEMBL5163388 | 0.82 | ALDH1A1 (0.54) | KMT2AALDH1A1CHATNPSR1PYGL | |
| SCHEMBL4847293 | 0.78 | ALDH1A1 (0.46) | TRPA1KMT2APOLBPKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239139-B1 | CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE | NINGBO COMBIREG PHARMACEUTICAL TECH CO LTD (CN) | 2020-10-28 | — | — | EP | disclosed |
| EP-3239139-A1 | CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE | Shenzhen Salubris Pharmaceuticals Co., Ltd (CN) | 2017-11-01 | — | — | EP | disclosed |
| EP-2612857-B1 | CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE | SHENZHEN SALUBRIS PHARM CO LTD (CN) | 2017-07-26 | — | — | EP | disclosed |
| US-9085605-B2 | Chemical synthesis and anti-tumor and anti-metastatic effects of dual functional conjugate | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2015-07-21 | — | — | US | disclosed |
| EP-2612857-A1 | CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE | Institute of Mataria Medica, Chinese Academy of Medical Sciences (CN) | 2013-07-10 | — | — | EP | disclosed |
| US-20130143826-A1 | CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2013-06-06 | — | — | US | disclosed |
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143826-A1 | CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE | PTMS, DNPEP, PAICS | TRPA1 4413/4885KMT2A 3430/4885POLB 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.