Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462094 | 0.87 | — | — | |
| SCHEMBL14167174 | 0.80 | FDPS (0.46) | FDPSALDH1A1SLC6A3CYP2C19TSHR | |
| SCHEMBL28853121 | 0.80 | TSHR (0.45) | FDPSALDH1A1SLC6A2SLC6A4CYP2C19 | |
| Carbamic Acid SCHEMBL9205535 | 0.78 | FDPS (0.43) | FDPSALDH1A1SLC6A3TSHRNOS1 | |
| Carbamic Acid SCHEMBL9755247 | 0.78 | FDPS (0.43) | FDPSALDH1A1SLC6A3CYP2C19TSHR | |
| SCHEMBL10716865 | 0.75 | FDPS (0.41) | FDPSALDH1A1SLC6A3TSHRHTT | |
| SCHEMBL474771 | 0.73 | — | — | |
| SCHEMBL247632 | 0.72 | — | — | |
| SCHEMBL8267525 | 0.72 | — | — | |
| Carbamic Acid SCHEMBL2360016 | 0.72 | GABRA5 (0.34) | ALDH1A1CYP2C19HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534139-A1 | NOVEL AMINOALKYL-OXAZOLE AND AMINOALKYL-THIAZOLE CARBOXYLIC ACID AMIDES AS REGENERATION-PROMOTING SUBSTANCES FOR SENSORY ORGANS AND POST-MITOTIC TISSUE | EMC Microcollections GmbH (DE) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011095338-A1 | NOVEL AMINOALKYL-OXAZOLE AND AMINOALKYL-THIAZOLE CARBOXYLIC ACID AMIDES AS REGENERATION-PROMOTING SUBSTANCES FOR SENSORY ORGANS AND POST-MITOTIC TISSUE | EMC MICROCOLLECTIONS GMBH (DE) | 2011-08-11 | — | — | WO | disclosed |
| WO-2010010288-A3 | ALKYL THIAZOLE CARBAMATE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010010288-A2 | ALKYLTHIAZOL CARBAMATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-01-28 | — | — | WO | disclosed |