SCHEMBL28853121

SCHEMBL28853121

C=CCc1nccs1.NC(=O)c1csnn1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
ALDH1A1 P00352 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FDPS P14324 1/20 0.33
MAPT P10636 5/20 0.32
TDP1 Q9NUW8 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
ADORA3 P0DMS8 1/20 0.31
MC4R P32245 1/20 0.31
ADRA1A P35348 1/20 0.31
MC3R P41968 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL2360596 0.80 FDPS (0.41) TSHRCYP2C19SLC6A2SLC6A4ALDH1A1
SCHEMBL28833686 0.77 ALDH1A1 (0.43) TSHRCYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL27938701 0.76 ALDH1A1 (0.35) CYP2C19ALDH1A1ATML3MBTL1MAPT
SCHEMBL157088 0.74
SCHEMBL462094 0.74
SCHEMBL14167174 0.69 FDPS (0.46) TSHRCYP3A4CYP2D6CYP2C19ALDH1A1
Carbamic Acid SCHEMBL9205535 0.64 FDPS (0.43) TSHRCYP3A4ALDH1A1FDPSMAPT
SCHEMBL474771 0.63
SCHEMBL28649503 0.63
SCHEMBL247632 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104663674-B Fungicide compound and mixture 杜邦公司 2017-11-03 CN disclosed