Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607288 | 1.00 | CYP3A4 (0.53) | CYP3A4ATMLMNACHRM2CYP1A2 | |
| SCHEMBL21591549 | 0.88 | LMNA (0.56) | CYP3A4LMNANAMPT | |
| SCHEMBL10397903 | 0.84 | PTAFR (0.54) | CYP3A4 | |
| SCHEMBL10397902 | 0.84 | PTAFR (0.54) | CYP3A4 | |
| SCHEMBL30336917 | 0.83 | CYP3A4 (0.53) | CYP3A4ATMNAMPTACACB | |
| SCHEMBL2679135 | 0.83 | LMNA (0.55) | CYP3A4LMNACHRM2CYP1A2CYP2D6 | |
| SCHEMBL8010171 | 0.81 | CYP3A4 (0.57) | CYP3A4LMNANAMPT | |
| SCHEMBL25034870 | 0.80 | ATM (0.48) | ATM | |
| SCHEMBL479925 | 0.78 | CYP3A4 (0.72) | CYP3A4LMNACYP1A2NAMPT | |
| SCHEMBL8897259 | 0.77 | ALDH1A1 (0.63) | CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3372281-B1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2021-07-07 | — | — | EP | disclosed |