Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336917 | 0.82 | CYP3A4 (0.53) | CYP3A4NAMPTPOLBRAB9A | |
| SCHEMBL11825264 | 0.81 | POLB (0.50) | CYP3A4NAMPTALDH1A1LMNAMAPT | |
| SCHEMBL11825259 | 0.81 | POLB (0.50) | CYP3A4NAMPTALDH1A1LMNAMAPT | |
| SCHEMBL479925 | 0.81 | CYP3A4 (0.72) | CYP3A4NAMPTALDH1A1LMNAMAPT | |
| SCHEMBL23607288 | 0.81 | CYP3A4 (0.53) | CYP3A4NAMPTLMNA | |
| SCHEMBL8897259 | 0.81 | ALDH1A1 (0.63) | CYP3A4ALDH1A1LMNAHTTPKM | |
| SCHEMBL23607289 | 0.81 | CYP3A4 (0.53) | CYP3A4NAMPTLMNA | |
| SCHEMBL9411102 | 0.81 | CYP3A4 (0.53) | CYP3A4NAMPTALDH1A1LMNAMAPT | |
| SCHEMBL21591549 | 0.80 | LMNA (0.56) | CYP3A4NAMPTLMNARAB9A | |
| SCHEMBL9439389 | 0.79 | CYP3A4 (0.59) | CYP3A4NAMPTALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057318-A | ANTAGONISTS OF PLATELET ACTIVATING FACTOR ACETHER | SANOFI (FR) | 2000-05-02 | — | — | US | disclosed |
| US-5891894-A | 2-AMINO OXAZOLE DERIVATIVES; ANTAGONISTS OF PLATELET ACTIVATING FACTOR USEFUL IN TREATMENT OF ASTHMA, INFLAMMATION, CARDIOVASCULAR DISORDERS, RENAL DISEASES, OR AS CONTRACEPTIVES | SANOFI (FR) | 1999-04-06 | — | — | US | disclosed |
| US-5891893-A | 5-AMINO-1,2,4-OXA(OR THIA)DIAZOLES; ANTAGONISTS OF PLATELET ACTIVATING FACTOR USEFUL IN TREATMENT OF ASTHMA, ALLERGIES, INFLAMMATION, CARDIOVASCULAR DISEASES, RENAL DISEASES, OR AS CONTRACEPTIVES | SANOFI (FR) | 1999-04-06 | — | — | US | disclosed |
| US-5780468-A | ANTAGONIST OF PLATELET ACTIVATING FACTOR | SANOFI (FR) | 1998-07-14 | — | — | US | disclosed |
| US-5470855-A | Anticoagulants | SANOFI (FR) | 1995-11-28 | — | — | US | disclosed |