Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361212 | 1.00 | METAP2 (0.31) | METAP2 | |
| SCHEMBL2359148 | 1.00 | METAP2 (0.31) | METAP2 | |
| SCHEMBL5048361 | 0.79 | CTSS (0.32) | — | |
| SCHEMBL2329732 | 0.78 | — | — | |
| SCHEMBL2326210 | 0.78 | — | — | |
| SCHEMBL2325675 | 0.78 | — | — | |
| SCHEMBL2325873 | 0.70 | CTSK (0.32) | — | |
| SCHEMBL3679774 | 0.68 | CYP1A2 (0.52) | — | |
| SCHEMBL4976854 | 0.67 | CTSK (0.39) | — | |
| SCHEMBL4976850 | 0.67 | CTSK (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081927-B1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2011-08-17 | — | — | EP | claimed |