Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406442 | 1.00 | CYP19A1 (0.46) | CYP19A1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23608948 | 0.86 | GPR55 (0.47) | CYP19A1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23609126 | 0.79 | CYP19A1 (0.40) | CYP19A1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6965842 | 0.76 | CYP19A1 (0.54) | CYP19A1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL23608969 | 0.75 | SMN1; SMN2 (0.40) | CYP19A1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23608968 | 0.74 | CYP19A1 (0.39) | CYP19A1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30998238 | 0.73 | SMN1; SMN2 (0.51) | KMT2AALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL23609006 | 0.72 | SMN1; SMN2 (0.44) | CYP19A1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6647469 | 0.72 | CYP19A1 (0.43) | CYP19A1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23875581 | 0.71 | CYP19A1 (0.51) | CYP19A1KMT2AALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |