Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406442 | 0.86 | CYP19A1 (0.46) | ALDH1A1HPGDKMT2ASMN1; SMN2CYP19A1 | |
| SCHEMBL23608970 | 0.86 | CYP19A1 (0.46) | ALDH1A1HPGDKMT2ASMN1; SMN2CYP19A1 | |
| SCHEMBL23608949 | 0.82 | CYP19A1 (0.44) | GPR55ALDH1A1HPGDKDM4ECYP19A1 | |
| SCHEMBL30406544 | 0.77 | CYP19A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2CYP19A1P4HTM | |
| SCHEMBL23609126 | 0.76 | CYP19A1 (0.40) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL23608969 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6965842 | 0.74 | CYP19A1 (0.54) | ALDH1A1KDM4EKMT2ASMN1; SMN2CYP19A1 | |
| SCHEMBL30998238 | 0.73 | SMN1; SMN2 (0.51) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL23608966 | 0.73 | CYP19A1 (0.40) | KMT2ASMN1; SMN2CYP19A1LMNAMEN1 | |
| SCHEMBL29973640 | 0.73 | CYP19A1 (0.40) | KMT2ASMN1; SMN2CYP19A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117592-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-04-20 | — | — | US | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117592-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX5 | GPR55 2280/4885ALDH1A1 203/4885HPGD 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.