Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.43 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609248 | 0.86 | TLR8 (0.45) | CYP19A1MAPK1CSNK2A2FGFR2KDR | |
| SCHEMBL23875506 | 0.86 | MAPT (0.51) | CYP19A1MAPK1CSNK2A2FGFR2KDR | |
| SCHEMBL23609486 | 0.81 | LMNA (0.49) | CYP19A1MAPK1CSNK2A2FGFR2KDR | |
| SCHEMBL23608966 | 0.81 | CYP19A1 (0.40) | CYP19A1MAPK1CSNK2A2FGFR2KDR | |
| SCHEMBL23608967 | 0.79 | QPCT (0.39) | CYP19A1MAPK1CSNK2A2FGFR2KDR | |
| SCHEMBL23609484 | 0.78 | HPGDS (0.38) | CYP19A1MAPK1CSNK2A2FGFR2KDR | |
| SCHEMBL23608891 | 0.78 | FPR3 (0.40) | CYP19A1MAPK1CSNK2A2FGFR2KDR | |
| SCHEMBL23609770 | 0.78 | CSNK2A2 (0.38) | CYP19A1MAPK1CSNK2A2FGFR2KDR | |
| SCHEMBL10836121 | 0.77 | NAMPT (0.61) | CYP19A1NAMPTKMT2AMEN1KDM4E | |
| SCHEMBL23608970 | 0.76 | CYP19A1 (0.46) | CYP19A1MAPK1CSNK2A2FGFR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021411-B1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-6326386-B1 | ANTICOAGULANT | GLAXO GROUP LIMITED (GB) | 2001-12-04 | — | — | US | disclosed |