Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506532 | 0.80 | CYP3A4 (0.42) | ALDH1A1HSD17B10SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL3789741 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HSD17B10SMN1; SMN2DPP4MAPT | |
| SCHEMBL7259314 | 0.76 | BCAT2 (0.57) | ALDH1A1SMN1; SMN2MAPTMAPK1PKM | |
| SCHEMBL15940153 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL1929405 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HSD17B10ADRB2PDCD1CD274 | |
| Propane SCHEMBL9646509 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HSD17B10SMN1; SMN2DPP4MAPT | |
| SCHEMBL13497804 | 0.73 | CD44 (0.46) | ALDH1A1HSD17B10MAPTMAPK1KDM4E | |
| Propane SCHEMBL10492409 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HSD17B10SMN1; SMN2DPP4MAPT | |
| SCHEMBL1406272 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HSD17B10SMN1; SMN2ADRB2DPP4 | |
| SCHEMBL27817250 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HSD17B10SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |