Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785700 | 0.86 | ALDH1A1 (0.39) | ALDH1A1HSD17B10L3MBTL1MAP4K4LTK | |
| SCHEMBL19787487 | 0.85 | TDO2 (0.44) | ALDH1A1HSD17B10TDO2TDP1DPP4 | |
| SCHEMBL3790019 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1 | |
| SCHEMBL3783842 | 0.83 | MAP4K4 (0.47) | ALDH1A1HSD17B10MAP4K4CYP3A4TDP1 | |
| SCHEMBL23609409 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10L3MBTL1MAPK13MAPK12 | |
| SCHEMBL15940153 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10L3MBTL1TDO2MAPK13 | |
| SCHEMBL8466087 | 0.78 | TSHR (0.48) | ALDH1A1HSD17B10L3MBTL1MAP4K4CYP3A4 | |
| SCHEMBL18509790 | 0.78 | ESR2 (0.42) | ALDH1A1HSD17B10TDO2CLK4CYP3A4 | |
| SCHEMBL6077764 | 0.78 | MAPT (0.44) | ALDH1A1HSD17B10L3MBTL1TDO2TDP1 | |
| SCHEMBL18634828 | 0.76 | ADORA2B (0.41) | ALDH1A1HSD17B10L3MBTL1TDO2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-4443447-A | Phenyl-substituted tricyclic antibacterial agents | RIKER LABORATORIES, INC. (US) | 1984-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885HSD17B10 1100/4885L3MBTL1 3838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.