Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23875506 | 0.89 | MAPT (0.51) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6965842 | 0.81 | CYP19A1 (0.54) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6648239 | 0.81 | CYP19A1 (0.62) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL23609248 | 0.80 | TLR8 (0.45) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL23875581 | 0.79 | CYP19A1 (0.51) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7138301 | 0.77 | CYP19A1 (0.67) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL25797518 | 0.77 | CYP19A1 (0.48) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL23861179 | 0.77 | CYP19A1 (0.54) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL23875613 | 0.75 | MAPT (0.45) | LMNANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL11653014 | 0.73 | L3MBTL1 (0.86) | LMNANPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |